鉴定一种由植物病原菌野油菜黄单胞菌产生的新型β-内酰胺酶。
Identification of a novel beta-lactamase produced by Xanthomonas campestris, a phytopathogenic bacterium.
作者信息
Weng S F, Chen C Y, Lee Y S, Lin J W, Tseng Y H
机构信息
Institute of Molecular Biology, National Chung Hsing University, Taichung 402, Taiwan, Republic of China.
出版信息
Antimicrob Agents Chemother. 1999 Jul;43(7):1792-7. doi: 10.1128/AAC.43.7.1792.
Abstract
The Xanthomonas campestris pv. campestris 11 chromosome encodes a periplasmic beta-lactamase of 30 kDa. Gene replacement and complementation confirmed the presence of this enzyme. Its deduced amino acid sequence shows identity and conserved domains between it and Stenotrophomonas maltophilia L2 and other Ambler class A/Bush group 2 beta-lactamases. Southern hybridization detected a single homologous fragment in each of 12 other Xanthomonas strains, indicating that the presence of a beta-lactamase gene is common among xanthomonads.
摘要
野油菜黄单胞菌野油菜致病变种11的染色体编码一种30 kDa的周质β-内酰胺酶。基因替换和互补实验证实了这种酶的存在。其推导的氨基酸序列显示，它与嗜麦芽窄食单胞菌L2及其他安布勒A类/布什2组β-内酰胺酶之间存在同源性和保守结构域。Southern杂交在其他12株黄单胞菌中均检测到一个单一的同源片段，表明β-内酰胺酶基因在黄单胞菌中普遍存在。
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