Dore M P, Graham D Y, Sepulveda A R, Realdi G, Osato M S
Department of Medicine, VA Medical Center, and Baylor College of Medicine, Houston, Texas 77030, USA.
Antimicrob Agents Chemother. 1999 Jul;43(7):1803-4. doi: 10.1128/AAC.43.7.1803.
The sensitivities to penicillins and to a penicillin and beta-lactamase inhibitor combination agent were determined for Helicobacter pylori strains that were sensitive, moderately resistant, or highly resistant to amoxicillin. All strains were resistant to nafcillin and oxacillin. Moderately resistant strains showed an intermediate zone of inhibition to ticarcillin, mezlocillin, piperacillin, and amoxicillin-clavulanic acid. High-level resistance was associated with the smallest zone size for all penicillins tested.
对阿莫西林敏感、中度耐药或高度耐药的幽门螺杆菌菌株测定了对青霉素以及青霉素与β-内酰胺酶抑制剂联合制剂的敏感性。所有菌株对萘夫西林和苯唑西林均耐药。中度耐药菌株对替卡西林、美洛西林、哌拉西林和阿莫西林-克拉维酸呈现中间抑菌圈。对所有测试的青霉素而言,高水平耐药与最小抑菌圈大小相关。