实体器官移植受者中抗人巨细胞病毒免疫球蛋白A（IgA）和免疫球蛋白M（IgM）抗体的长期持续存在情况。
Long-term persistence of immunoglobulin A (IgA) and IgM antibodies against human cytomegalovirus in solid-organ transplant recipients.
作者信息
Eing B R, Baumeister H G, Kuehn J E, May G
机构信息
Institute of Medical Microbiology, Clinical Virology, University of Muenster, Muenster, Germany.
出版信息
Clin Diagn Lab Immunol. 1999 Jul;6(4):621-3. doi: 10.1128/CDLI.6.4.621-623.1999.
Abstract
The retrospective analysis of 494 solid-organ transplant recipients revealed that during the follow-up period (mean duration, 3.2 years) 184 (88%) of 209 anti-human cytomegalovirus (HCMV) immunoglobulin A (IgA)-positive patients remained IgA positive, as did 128 (74.85%) of 171 anti-HCMV IgM-positive patients. We conclude that anti-HCMV IgA and IgM testing for management of clinically relevant HCMV infections in solid-organ transplant recipients is dispensable.
摘要
对494名实体器官移植受者的回顾性分析显示，在随访期（平均时长3.2年）内，209名抗人巨细胞病毒（HCMV）免疫球蛋白A（IgA）阳性患者中有184名（88%）仍为IgA阳性，171名抗HCMV IgM阳性患者中有128名（74.85%）也是如此。我们得出结论，对于实体器官移植受者中临床相关HCMV感染的管理，检测抗HCMV IgA和IgM是不必要的。
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