Kinloch D
University of Arkansas for Medical Sciences, College of Nursing, Little Rock, USA.
Am J Crit Care. 1999 Jul;8(4):231-40; quiz 241-2.
Instillation of normal saline before endotracheal suctioning is thought to facilitate removal of secretions and ultimately to improve the patient's oxygenation status. To date, no studies have used an in vivo measure of oxygenation such as mixed venous oxygen saturation to characterize the effects of instillation of normal saline.
To describe the effects of instillation of normal saline into an endotracheal tube before suctioning on mixed venous oxygen saturation in critically ill adult patients.
In a descriptive, observational study, 35 patients were assigned to either of 2 groups after coronary artery bypass grafting. One group had 5 mL of normal saline instilled at the start of endotracheal tube suctioning; the other group had the same endotracheal tube suctioning procedure without the use of saline. Data on mixed venous oxygen saturation were recorded at 1-minute intervals for a 5-minute baseline period and then throughout the suctioning procedure until mixed venous oxygen saturation returned to baseline levels.
The time required for mixed venous oxygen saturation to return to baseline values after suctioning was an average of 3.78 minutes longer when saline was used.
Instillation of normal saline before endotracheal suctioning has an adverse effect on oxygenation as indicated by mixed venous oxygen saturation. This finding contradicts the assumption that instillation of normal saline improves oxygenation status.
气管内吸痰前滴注生理盐水被认为有助于分泌物清除,并最终改善患者的氧合状态。迄今为止,尚无研究使用如混合静脉血氧饱和度这样的体内氧合指标来描述滴注生理盐水的效果。
描述成年危重症患者在吸痰前向气管内导管滴注生理盐水对混合静脉血氧饱和度的影响。
在一项描述性观察研究中,35例冠状动脉搭桥术后患者被分为两组。一组在气管内导管吸痰开始时滴注5ml生理盐水;另一组采用相同的气管内吸痰操作,但不使用生理盐水。在5分钟的基线期以1分钟的间隔记录混合静脉血氧饱和度数据,然后在整个吸痰过程中持续记录,直到混合静脉血氧饱和度恢复到基线水平。
使用生理盐水时,吸痰后混合静脉血氧饱和度恢复到基线值所需的时间平均延长3.78分钟。
如混合静脉血氧饱和度所示,气管内吸痰前滴注生理盐水对氧合有不利影响。这一发现与滴注生理盐水可改善氧合状态的假设相矛盾。