Mouchamps E, Gaspard U
Centre de la Ménopause du CHU au Sart Tilman.
Rev Med Liege. 1999 May;54(5):489-94.
Physicians or gynaecologists, specifically in their general practice or in the setting of a menopause clinic, are more and more frequently confronted to sexual complaints of menopausal women. Among these, decline in sexual desire is probably the most usually reported. The first study to evaluate a potential relationship between sexual functioning and menopause was conducted by Hallström in 1977. Thereafter, a review of the literature was able to show that there is nearly a consensus regarding the role of oestrogens in that condition. They effectively relieve vaginal atrophy and resulting dyspareunia. There is less agreement, however, regarding a direct effect of oestrogens on more complex sexual behaviour and motivation. When analyzing potential influence of sex hormones, oestrogens may exert a positive effect on the quality of the sexual relationship whereas androgens can definitely increase sexual "motivation" including sexual desire. In spite of the potentially important part played by androgens as promoters of libido and in the maintenance of sexual functioning in men and women, the exact role of the hormonal treatment in relieving sexual complaints still keeps controversial. In some women whose decline of sexual desire can be reasonably attributed to menopause, androgens in non-masculinizing adequate dosages, can be effectively included in the postmenopausal hormone replacement regimen. However, aetiology of diminished sexual motivation and desire is far from univocal particularly in the human being where psychological, social and cultural influences are endowed with a prominent importance. It is accordingly conspicuous that our sexual life is not reduced to hormonal fluctuations only. A short critical review of the literature devoted to the main aspects of changes of sexual desire associated with menopause is presented.
内科医生或妇科医生,特别是在其普通门诊或更年期诊所工作时,越来越频繁地面对更年期女性的性方面的诉求。其中,性欲下降可能是最常被报告的。1977年,霍尔斯特伦进行了第一项评估性功能与更年期之间潜在关系的研究。此后,文献综述表明,关于雌激素在这种情况下的作用几乎达成了共识。它们能有效缓解阴道萎缩及由此导致的性交困难。然而,对于雌激素对更复杂的性行为和动机的直接影响,人们的意见分歧较大。在分析性激素的潜在影响时,雌激素可能对性关系质量产生积极影响,而雄激素肯定能增强性“动机”,包括性欲。尽管雄激素在促进性欲和维持男性及女性性功能方面可能发挥重要作用,但激素治疗在缓解性方面诉求的确切作用仍存在争议。在一些性欲下降可合理归因于更年期的女性中,非男性化的适当剂量的雄激素可有效纳入绝经后激素替代方案。然而,性动机和欲望减退的病因远非单一的,尤其是在人类中,心理、社会和文化影响具有显著重要性。因此,很明显我们的性生活不仅仅受激素波动影响。本文对与更年期相关的性欲变化主要方面的文献进行了简要批判性综述。