Murakami N, Furuto-Kato S, Fujisawa I, Ohyama K, Nakao S, Kuwayama A, Kageyama N
Department of Internal Medicine, Kishiwada City Hospital, Kishiwada, Japan.
Endocr J. 1998 Oct;45(5):631-6. doi: 10.1507/endocrj.45.631.
There has been accumulating evidence that pituitary adenomas which cause Cushing's disease are located not only in sella turcica but also in various extrasellar and intracranial regions. We describe a case of Cushing's disease caused by a supra- and extrasellar ACTH-producing microadenoma, which originated in the anterior pituitary and extended upward without connecting to the stalk. The pituitary microadenoma was identified and removed by transsphenoidal microsurgery. After the surgery the patient experienced complete remission. This type of pituitary microadenoma is considered to be rare, but in order to accomplish successful surgical treatment, it is necessary to consider that pituitary adenomas which cause Cushing's disease may be located in such an unusual position.
越来越多的证据表明，导致库欣病的垂体腺瘤不仅位于蝶鞍内，还位于各种鞍外和颅内区域。我们描述了一例由鞍上和鞍外产生促肾上腺皮质激素（ACTH）的微腺瘤引起的库欣病病例，该微腺瘤起源于垂体前叶并向上延伸而未与垂体柄相连。通过经蝶窦显微手术识别并切除了垂体微腺瘤。术后患者实现了完全缓解。这种类型的垂体微腺瘤被认为很罕见，但为了实现成功的手术治疗，有必要考虑到导致库欣病的垂体腺瘤可能位于如此不寻常的位置。
