马西霉素B，一种来自放线菌HIL Y - 8620959的新型抗真菌大环内酯。

Mathemycin B, a new antifungal macrolactone from actinomycete species HIL Y-8620959.

作者信息

Mukhopadhyay T, Nadkarni S R, Bhat R G, Gupte S V, Ganguli B N, Petry S, Kogler H

机构信息

Research Centre, Hoechst Marion Roussel Ltd., Mulund (W), Mumbai 400 080, India.

出版信息

J Nat Prod. 1999 Jun;62(6):889-90. doi: 10.1021/np980369q.

DOI:10.1021/np980369q

PMID:10395510

Abstract

A new macrocyclic lactone antibiotic mathemycin B (1) was isolated from the fermentation broth of an Actinomycete sp. culture Y-8620959. The structure of 1 was elucidated by high-resolution MS and interpretation of 2D NMR results. Mathemycin B is active against a variety of phytopathogenic organisms.

摘要

一种新的大环内酯类抗生素马瑟霉素B（1）从放线菌属菌株Y-8620959的发酵液中分离得到。通过高分辨率质谱和二维核磁共振结果的解析确定了1的结构。马瑟霉素B对多种植物病原生物具有活性。