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[具有非典型部位且对环孢素A反应迅速的坏疽性脓皮病]

[Pyoderma gangrenosum with an atypical location and a rapid response to cyclosporin A].

作者信息

Ferrer Ríos T, Ramos Lora M, Pallarés Manrique H, Pérez Gómez M B, Garrido Mora M, Carrasco F J, Domínguez Macías A

机构信息

Sección de Aparato Digestivo, Hospital Juan Ramón Jiménez, Huelva.

出版信息

Gastroenterol Hepatol. 1999 May;22(5):227-9.

Abstract

Pyoderma gangrenosum is an unusual neutrophilic dermatosis associated to different rheumatologic, haematologic and inflammatory bowel diseases which generally responds to the therapy of the underlying disease. We report a case of pyoderma in a 44-years-old woman with paucisymptomatic, distal, ulcerative colitis which appeared simultaneously in her forehead and hands. We think it of general interest because of its localization, its importance, the failure of response to steroids and the need of cyclosporine A for regression.

摘要

坏疽性脓皮病是一种罕见的嗜中性皮病,与不同的风湿性、血液学和炎症性肠病相关,通常对基础疾病的治疗有反应。我们报告一例44岁女性的坏疽性脓皮病,该患者患有症状轻微的远端溃疡性结肠炎,其前额和手部同时出现病变。鉴于其病变部位、严重性、对类固醇治疗无反应以及需要使用环孢素A才能消退,我们认为该病例具有普遍意义。

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