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[溃疡性结肠炎合并坏疽性脓皮病]

[Ulcerative colitis associated with pyoderma gangrenosum].

作者信息

Tusnádi A, Uhrin K, Bényei M, Krasznai G

机构信息

Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelöintézet, Szolnok.

出版信息

Orv Hetil. 1994 Apr 24;135(17):917-9.

PMID:7909938
Abstract

The authors present a 42-year-old man's case in whom the onset of chronic ulcerative colitis and pyoderma gangrenosum was simultaneous. Pyoderma gangrenosum began as bullae on his chest and lower limb. The main symptoms were fever, anaemia, hypoproteinaemia beyond the skin lesions, and the abdominal symptoms characterizing chronic ulcerative colitis were absent. The thorough internal check-up and the micribiologic and histologic examinations of the skin disorders made clear that the lesions mentioned were the skin symptoms of a systemic disease. Sulfasalazin and prednisolone therapy of the underlying disease and the local non-specific treatment of the cutaneous lesions resulted together in the patient's rapid improvement. The authors give a brief review of pyoderma gangrenosum and of the connection between pyoderma gangrenosum and chronic ulcerative colitis.

摘要

作者报告了一名42岁男性病例,其慢性溃疡性结肠炎和坏疽性脓皮病同时发病。坏疽性脓皮病最初表现为胸部和下肢的大疱。主要症状为发热、贫血、皮肤病变以外的低蛋白血症,且无慢性溃疡性结肠炎的腹部症状。全面的内科检查以及皮肤疾病的微生物学和组织学检查明确显示,上述病变是一种全身性疾病的皮肤症状。对基础疾病采用柳氮磺胺吡啶和泼尼松龙治疗,同时对皮肤病变进行局部非特异性治疗,共同促使患者迅速康复。作者简要回顾了坏疽性脓皮病以及坏疽性脓皮病与慢性溃疡性结肠炎之间的关联。

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