Perrone C, Pasquetto G, Boschello M, Dovigo P, Marchiori M C, Galassi A, De Dominicis E
Divisione di Cardiologia, UCIC, Ospedale Cazzavillan, Arzignano, VI.
G Ital Cardiol. 1999 Jun;29(6):662-8.
Free-wall rupture of the heart is the second most common cause of death in acute myocardial infarction (AMI), following pump failure. Acute rupture is more common and rapidly fatal, while subacute rupture, which accounts for about 30% of total cases of mortality in AMI, can be diagnosed early by clinical signs with the support of echocardiography in coronary intensive care units.
From March 1996 to December 1997, 293 patients diagnosed with acute myocardial infarction were admitted to the coronary intensive care unit of our hospital. Of these patients, 71 (23.8%) were treated with thrombolysis within 6 hours of onset of symptoms. All patients were observed daily with M-2D color Doppler echocardiography and in the event of renewed chest pain, electrocardiogram changes, abrupt hypotension, syncope or clinical signs of low output syndrome.
We observed 11 cases (3.8%) of free-wall rupture of the heart in acute myocardial infarction with echocardiography, 6 females and 5 males, with a mean age of 74.2 +/- 7.8 years (min. 56-max 84), none of whom had prior AMI. Six of them received thrombolytic therapy, six were hypertensive (54.5%) and three were diabetics (27.2%). Surgical repair was performed in two patients with subacute rupture, but one died a few days later. The echocardiography data at bedside for diagnosis of cardiac rupture were confirmed in 5 patients with autopsy and intraoperatively in two of them.
Routine use of echocardiography in coronary intensive care units allows prompt diagnosis of cardiac rupture in acute myocardial infarction, and in the event of subacute rupture it can accelerate surgical decision-making.
心脏游离壁破裂是急性心肌梗死(AMI)中仅次于泵衰竭的第二大常见死因。急性破裂更为常见且迅速致命,而亚急性破裂约占AMI总死亡病例的30%,在冠状动脉重症监护病房中,借助超声心动图的支持,可通过临床体征早期诊断。
1996年3月至1997年12月,293例诊断为急性心肌梗死的患者入住我院冠状动脉重症监护病房。其中71例(23.8%)在症状发作6小时内接受了溶栓治疗。所有患者每日均接受M-2D彩色多普勒超声心动图检查,若出现再次胸痛、心电图改变、突然低血压、晕厥或低输出量综合征的临床体征,则进行检查。
通过超声心动图,我们观察到11例(3.8%)急性心肌梗死患者发生心脏游离壁破裂,其中女性6例,男性5例,平均年龄74.2±7.8岁(最小56岁 - 最大84岁),均无前壁心肌梗死病史。其中6例接受了溶栓治疗,6例为高血压患者(54.5%),3例为糖尿病患者(27.2%)。2例亚急性破裂患者接受了手术修复,但其中1例在数日后死亡。5例经尸检确诊心脏破裂的患者以及其中2例术中患者的床旁超声心动图诊断数据得到了证实。
在冠状动脉重症监护病房常规使用超声心动图可及时诊断急性心肌梗死中的心脏破裂,对于亚急性破裂情况,它可加速手术决策。