Lukac P, Kofler K, Waldhör T, Steinbach K
Ludwig-Boltzmann-Institut für Arrhythmieforschung 3. Medizinische Abteilung mit Kardiologie Wilhelminenspital der Stadt Wien, Osterreich.
Z Kardiol. 1996 Oct;85(10):776-81.
In a retrospective study including 1888 consecutive patients (pts) with acute myocardial infarction (AMI) admitted in the years 1989-1993 to the CCU, the relationship between sex, age, history of angina, location of infarction and heart wall rupture has been studied in a multivariate regression model. Female sex (p = 0.0013), older age (p = 0.0001), first angina during the AMI (p = 0.001) were indicative for significantly higher risk of rupture. Women are at higher risk only with anterior wall AMI (p = 0.0393). This risk increases continually with age, more in pts with inferior wall AMI than anterior wall AMI (p = 0.339). Females over the age of 75 with anterior wall AMI and first AP, and males and females over 83 with inferior wall AMI and first AP are at the highest risk of rupture (48.6% of deaths). We conclude that the defined high risk pts should be carefully monitored concerning the signs of impending heart wall rupture.
在一项回顾性研究中，纳入了1989年至1993年期间连续入住冠心病监护病房（CCU）的1888例急性心肌梗死（AMI）患者，在多变量回归模型中研究了性别、年龄、心绞痛病史、梗死部位与心脏壁破裂之间的关系。女性（p = 0.0013）、年龄较大（p = 0.0001）、AMI期间首次发生心绞痛（p = 0.001）表明破裂风险显著更高。仅在前壁AMI时女性风险更高（p = 0.0393）。这种风险随年龄持续增加，下壁AMI患者比前壁AMI患者增加得更多（p = 0.339）。年龄超过75岁的前壁AMI且首次发生心绞痛的女性，以及年龄超过83岁的下壁AMI且首次发生心绞痛的男性和女性，破裂风险最高（死亡病例的48.6%）。我们得出结论，对于确定的高危患者，应密切监测即将发生心脏壁破裂的迹象。
