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[西伯利亚东北部原住民中类风湿关节炎及类风湿因子的患病率]

[The prevalence of rheumatoid arthritis and the rheumatoid factor in the native inhabitants of northeastern Siberia].

作者信息

Erdes Sh, Alekseeva L I, Krylov M Iu, Kariakin A N, Benevolenskaia L I

出版信息

Ter Arkh. 1999;71(5):9-12.

Abstract

AIM

The study of rheumatoid arthritis (RA) and rheumatoid factor (RF) prevalence among residents of eastern Chukotka--Eskimos and Chukchi.

MATERIALS AND METHODS

Simultaneous total survey covered 974 of 1176(83.3%) residents of 4 villages in the eastern Chukotka.

RESULTS

RA was diagnosed in 7(0.7%) examines. Clinical picture of the disease was characterized by for the most part symmetric affection of hand and feet joints, absence of systemic manifestations, favourable course and frequent absence of RF. RF positive titers (1:160 and higher) occurred in 23 of 804 examinees (2.9%), among Eskimos--6%. This was significantly higher than in Chukchi (2.0%) and in subjects of mixed nationality (1.3%).

CONCLUSION

Prevalence and clinical picture of RA in residents of northeast Siberia were comparable with such observed in other epidemiological surveys in Russia and Alaska.

摘要

目的

研究楚科奇东部居民(爱斯基摩人和楚科奇人)中类风湿性关节炎(RA)及类风湿因子(RF)的患病率。

材料与方法

对楚科奇东部4个村庄的1176名居民中的974人(83.3%)进行了同步全面调查。

结果

7名(0.7%)受检者被诊断为RA。该病的临床表现大多为手足关节对称性受累,无全身表现,病程良好且RF常为阴性。804名受检者中有23名(2.9%)RF滴度呈阳性(1:160及以上),其中爱斯基摩人中有6%呈阳性。这显著高于楚科奇人(2.0%)和混血族裔(1.3%)。

结论

西伯利亚东北部居民中RA的患病率及临床表现与俄罗斯和阿拉斯加其他流行病学调查中观察到的情况相当。

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