Lawrence R C, Everett D F, Benevolenskaya L I, Boyer G S, Erdesz S, Templin D W, Alexeeva L I, Lanier A P, Cornoni-Huntley J C, Mylov N M, Heyse S
National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.
Arctic Med Res. 1996 Oct;55(4):187-94.
Parallel epidemiologic studies of spondyloarthropathy in aboriginal circumpolar populations were carried out by U.S. and Russian investigators. These complementary studies used the same data collection instrument and disease criteria to facilitate comparisons. During three expeditions to Siberia, Russian investigators collected cross-sectional data from four settlements of Eskimos and Chukchi Indians on the Chukotka peninsula for a study of disease prevalence. U.S. researchers collected cross-sectional data from Eskimos in four Alaskan regions for studies of prevalence and longitudinal data for studies of clinical manifestations, natural history, disease impact, and health care utilization. The aims of these studies were to describe the spectrum of spondyloarthropathy in these populations, and to lay the groundwork for investigations of the role of specific genetic and environmental factors in the pathogenesis and expression of disease. These studies were carried out with a minimum disruption to the native people.
美国和俄罗斯的研究人员对北极圈原住民族群中的脊柱关节病进行了平行流行病学研究。这些互补性研究使用相同的数据收集工具和疾病标准，以利于比较。在三次前往西伯利亚的考察中，俄罗斯研究人员从楚科奇半岛上四个爱斯基摩人和楚科奇印第安人定居点收集了横断面数据，用于疾病患病率研究。美国研究人员从阿拉斯加四个地区的爱斯基摩人那里收集了横断面数据用于患病率研究，并收集了纵向数据用于临床表现、自然史、疾病影响及医疗保健利用情况的研究。这些研究的目的是描述这些人群中脊柱关节病的范围，并为调查特定基因和环境因素在疾病发病机制和表现中的作用奠定基础。这些研究在对原住民干扰最小的情况下进行。
