[The evaluation of hemostatic disorders in patients with systemic lupus erythematosus].

AIM

Assessment of hemostasis in SLE patients.

MATERIALS AND METHODS

We studied different coagulation parameters such as activated partial thromboplastin time (APTT), thrombin time (TT), prothrombin time (PT), activated clotting time (ACT); platelet aggregation (spontaneous and induced), fibrinolytic activity, concentration of fibrinogen, fibrinogen degradation products (FDP) and serotonin.

RESULTS

Coagulation abnormalities were found with prevalence of hypercoagulation in APTT and TT tests. Fibrinolysis was inhibited. Levels of serotonin, FDP and spontaneous aggregation activity significantly increased.

CONCLUSION

The above changes were typical for lingering DIC syndrome.