Arshinov A V, Lapin V A, Raĭt Iu A
Ter Arkh. 1999;71(5):38-40.
Assessment of hemostasis in SLE patients.
We studied different coagulation parameters such as activated partial thromboplastin time (APTT), thrombin time (TT), prothrombin time (PT), activated clotting time (ACT); platelet aggregation (spontaneous and induced), fibrinolytic activity, concentration of fibrinogen, fibrinogen degradation products (FDP) and serotonin.
Coagulation abnormalities were found with prevalence of hypercoagulation in APTT and TT tests. Fibrinolysis was inhibited. Levels of serotonin, FDP and spontaneous aggregation activity significantly increased.
The above changes were typical for lingering DIC syndrome.
评估系统性红斑狼疮（SLE）患者的止血情况。
我们研究了不同的凝血参数，如活化部分凝血活酶时间（APTT）、凝血酶时间（TT）、凝血酶原时间（PT）、活化凝血时间（ACT）；血小板聚集（自发和诱导）、纤溶活性、纤维蛋白原浓度、纤维蛋白原降解产物（FDP）和5-羟色胺。
在APTT和TT检测中发现凝血异常，以高凝状态为主。纤溶受到抑制。5-羟色胺、FDP水平及自发聚集活性显著升高。
上述变化是持续性弥散性血管内凝血（DIC）综合征的典型表现。
