Agarwal K, Narayan S, Kumari S, Agarwal A K
Department of Pathology, Lady Hardinge Medical College and Associated Hospitals, New Delhi.
J Indian Med Assoc. 1998 Jun;96(6):171-3.
Abnormalities in coagulation profile were correlated with clinical outcome in neonates (n = 30) of mothers with pregnancy induced hypertension (PIH). Same number of neonates born to normotensive mothers was taken as control. Significant correlation was observed between decreasing gestational age and alterations in all coagulation parameters. Higher incidence of prematurity, hyperbilirubinaemia and significant prolongation in partial thromboplastin time with kaolin (PTTK) and thrombin time (TT) values were observed with increasing severity of PIH. Incidence of disseminated intravascular coagulation (DIC) was higher in preterm neonates than in term neonates.
患有妊娠高血压综合征（PIH）的母亲所生新生儿（n = 30）的凝血指标异常与临床结局相关。选取相同数量血压正常母亲所生的新生儿作为对照。观察到胎龄降低与所有凝血参数改变之间存在显著相关性。随着PIH严重程度增加，早产、高胆红素血症的发生率更高，高岭土部分凝血活酶时间（PTTK）和凝血酶时间（TT）值显著延长。早产儿弥散性血管内凝血（DIC）的发生率高于足月儿。
