Barry B, Géhanno P
Service ORL, Hôpital Bichat-Claude Bernard, Paris.
Ann Otolaryngol Chir Cervicofac. 1999 Jun;116(3):149-53.
The link between the occurrence of a SCC in the head and neck and human immunodeficiency virus infection is controversial.
A survey of specialists in France was carried out in 1995 to investigate it's incidence since the start of the epidemic.
Twenty one patients (sex ratio 20/1) with concomitant HIV infection and SCC of the head and neck were evaluated. The age distribution ranged from 30 to 63 with a mean of 44 years-old. Twelve patients were under 45 years-old. There was no obvious relationship between any peculiar risk group for HIV infection and occurrence of a SCC. At the time of diagnosis of their carcinoma 10 patients had clinical and/or biological features for AIDS. Alcohol and tobacco consumption were present in twelve patients, moderate in four and absent in five patients. Oropharyngeal carcinoma was frequent in patients without risk factors and immunodepression.
The high rate of young adults and patients with no or moderate risk factors for SCC suggests that SCC could be related to HIV infection.
头颈部鳞状细胞癌(SCC)的发生与人类免疫缺陷病毒(HIV)感染之间的联系存在争议。
1995年对法国的专家进行了一项调查,以研究自该流行病开始以来其发病率。
对21例同时感染HIV和头颈部SCC的患者(性别比为20/1)进行了评估。年龄分布在30岁至63岁之间,平均年龄为44岁。12例患者年龄在45岁以下。HIV感染的任何特定风险组与SCC的发生之间均无明显关系。在诊断出癌症时,10例患者具有艾滋病的临床和/或生物学特征。12例患者有饮酒和吸烟情况,4例为中度,5例无此情况。口咽癌在无危险因素和免疫抑制的患者中很常见。
SCC患者中年轻人以及无或有中度危险因素的患者比例较高,这表明SCC可能与HIV感染有关。