[Specific aspects of the nervous system and brain blood supply in women during prolonged anti-orthostatic hypokinesia].

The nervous system and cerebral hemodynamics studies of eight essentially healthy female test-subjects during the 120-d head-down bed rest included analysis of life history and monthly clinical/neurophysiological examinations (neurological testing, REG, Doppler ultrasound investigation of main arteries of the head). Altered positioning of the head and prolonged bed rest were shown to incur the risk of insufficient cerebral circulation. Most often hemodynamic deviations were observed in the vertebrobasilar basin consequent to the experimental conditions and specifics of the anatomical site of the vertebral arteries in the bony vertebral canal; clinically they were manifested by involvement of truncal structures of the brain. The second month of bed rest should be considered critical because of the evidence of the unstable neurological microsymptomatology implying hemodynamic shifts in the main cerebral arteries by the time. Physical exercises during bed rest slacken the pace of cerebral hemodynamics deviations.