Lisowska-Myjak B
Katedry i Zakładu Biochemii i Chemii Klinicznej, Akademii Medycznej w Warszawie.
Neurol Neurochir Pol. 1999 Jan-Feb;33(1):143-9.
The balance between proteinases and their inhibitors is important in maintaining structural integrity of connective tissues, including the arterial wall. Elevated serum elastase level is a possible serum marker of patients with high risk of aneurysm formation. Possibly, the heterozygous and the homozygous AAT deficiency states are genetic risk factors that could predispose a aneurysm formation.
蛋白酶与其抑制剂之间的平衡对于维持包括动脉壁在内的结缔组织的结构完整性至关重要。血清弹性蛋白酶水平升高可能是动脉瘤形成高危患者的血清标志物。杂合子和纯合子α1抗胰蛋白酶缺乏状态可能是易患动脉瘤形成的遗传危险因素。