Grouhi M, Alshehri M, Hummel D, Roifman C M
University of Toronto, The Hospital for Sick Children, Division of Immunology/Allergy, Toronto, Ontario, Canada.
J Allergy Clin Immunol. 1999 Jul;104(1):190-3. doi: 10.1016/s0091-6749(99)70134-x.
Anaphylaxis is the most urgent clinical immunologic event. Effective treatment is best achieved by administration of epinephrine. Accidental exposure to the responsible allergen is the most common cause of anaphylaxis, and because it could be fatal within minutes, epinephrine in preloaded syringes and auto-injectors has been introduced. In our experience patients and medical personnel are not familiar with the use of this device.
We sought to assess community-based professionals' knowledge of epinephrine auto-injector use and their ability to educate patients.
Study participants consisted of a medical convention's delegates and emergency department personnel in metropolitan Toronto, as well as pharmacists of the target hospitals and retail pharmacists. Research assistants approached eligible professionals to fill out a questionnaire and demonstrate their ability to use a standard placebo auto-injector trainer.
A total of 122 professionals (composed of emergency physicians, family practitioners, and pediatricians) consented to participate in this study. The majority of participants (81%) did not have a placebo trainer to educate their patients; 76% did not know the 2 available dose strengths. To provide instructions and reinforcement, physicians clearly must have the necessary skills and knowledge, yet only 25% of the study participants were able to demonstrate the 3 steps of injection correctly.
Our study highlights a specific and important deficiency in medical professionals' care of patients at risk for anaphylaxis. The results challenge the current methods of educating professionals, as well as patients, when prescribing or using epinephrine auto-injectors. Clearly a new approach to educating and maintaining such skills is required.
过敏反应是最紧急的临床免疫事件。通过注射肾上腺素可实现最佳有效治疗。意外接触致敏原是过敏反应最常见的原因,由于过敏反应可能在数分钟内致命,预充式注射器和自动注射器中的肾上腺素已被采用。根据我们的经验,患者和医务人员对该设备的使用并不熟悉。
我们试图评估社区专业人员对肾上腺素自动注射器使用的了解程度及其对患者进行教育的能力。
研究参与者包括多伦多市一个医学会议的代表、急诊科人员、目标医院的药剂师以及零售药剂师。研究助理联系符合条件的专业人员填写问卷,并展示他们使用标准安慰剂自动注射器训练器的能力。
共有122名专业人员(包括急诊医生、家庭医生和儿科医生)同意参与本研究。大多数参与者(81%)没有安慰剂训练器来对患者进行培训;76%的人不知道有两种可用的剂量强度。为了提供指导和强化培训,医生显然必须具备必要的技能和知识,但只有25%的研究参与者能够正确演示注射的三个步骤。
我们的研究突出了医疗专业人员在照顾有过敏反应风险患者方面存在的一个特定而重要的不足。研究结果对目前在开具或使用肾上腺素自动注射器时对专业人员以及患者进行教育的方法提出了挑战。显然需要一种新的方法来进行教育并维持这些技能。