Tepas J J, MacLean W C, Kolbach S, Shermeta D W
J Pediatr Surg. 1978 Dec;13(6D):622-6. doi: 10.1016/s0022-3468(78)80104-3.
Absorption studies in rats have shown that intestinal adaptation after catastrophic injury can be stimulated by early enteral feeding. Using this concept, we have devised a technique of early initiation and advancement of oral feedings that begins with Cho-Free and Polycose and gradually adds sucrose and MCT in increasing proportions. The increasing complexity and caloric density of this diet provide sufficient nutrition to allow weaning from total parenteral alimentation within 2--3 wk. Our preliminary experience in babies with midgut volvulus, necrotizing enterocolitis, and gastroschisis has been successful and uncomplicated. These patients have demonstrated consistent weight gain and have been spared the complications associated with prolonged parenteral alimentation.
对大鼠的吸收研究表明,严重损伤后的肠道适应性可通过早期肠内喂养来刺激。基于这一概念,我们设计了一种早期开始并推进口服喂养的技术,该技术从无胆碱饮食和聚葡萄糖开始,然后逐渐按比例增加蔗糖和中链甘油三酯。这种饮食的复杂性和热量密度不断增加,可提供足够的营养,使患者在2至3周内从全胃肠外营养断奶。我们在患有中肠扭转、坏死性小肠结肠炎和腹裂的婴儿身上的初步经验是成功且无并发症的。这些患者体重持续增加,避免了与长期肠外营养相关的并发症。