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核医学进展:当前概念

Advances in nuclear medicine: current concepts.

作者信息

Noto R B, Scheiner J D

机构信息

Brown University School of Medicine/Rhode Island Hospital, Providence, RI 02903, USA.

出版信息

Med Health R I. 1999 Jun;82(6):190-4.

PMID:10402834
Abstract

As described above, many scintigraphic studies have recently become available which provide vital clinical information in a wide variety of diseases. The future of nuclear medicine also appears bright. Modifications to current gamma cameras will likely occur in the next few years to replace sodium iodide crystals with new scintillators like oxyorthosilicates which have better imaging characteristics for both single photon and positron-emitting radionuclides. Ongoing computer improvements will allow improved reconstruction and processing with newer systems already capable of advanced iterative reconstruction algorithms. Development of new radiopharmaceuticals is progressing at a rapid pace, with emphasis on new tracers that can provide information about diseases at the molecular level, such as receptor imaging agents. In addition, radiolabeled tracers for therapeutic purposes will continue to progress, including monoclonal antibodies labeled with beta emitters. Overall, nuclear medicine will continue to evolve in many new directions and provide useful functional imaging data about a variety of different organ systems and diseases.

摘要

如上所述,最近有许多闪烁扫描研究可供使用,这些研究在多种疾病中提供了至关重要的临床信息。核医学的未来似乎也很光明。在未来几年,当前的伽马相机可能会进行改进,用新型闪烁体如正硅酸氧取代碘化钠晶体,这些新型闪烁体对单光子和正电子发射放射性核素都具有更好的成像特性。计算机技术的不断进步将使更新系统的重建和处理得到改进,这些系统已经能够使用先进的迭代重建算法。新型放射性药物的研发正在迅速推进,重点是能够在分子水平提供疾病信息的新型示踪剂,如受体显像剂。此外,用于治疗目的的放射性标记示踪剂也将继续发展,包括用β发射体标记的单克隆抗体。总体而言,核医学将继续朝着许多新方向发展,并提供有关各种不同器官系统和疾病的有用功能成像数据。

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