Kurosaka D, Ando I, Kato K, Oshima T, Kurosaka H, Yoshino M, Nagamoto T, Ando N
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
J Cataract Refract Surg. 1999 Jul;25(7):930-5. doi: 10.1016/s0886-3350(99)00078-4.
To determine whether the pathogenesis of capsule contraction syndrome involves the outgrowth of the fibrous membrane from the anterior capsule margin.
Department of Ophthalmology, Keio University School of Medicine, Tokyo, and the Ando Eye Clinic, Kanagawa, Japan.
A retrospective review of medical records and slitlamp photographs was conducted in 12 eyes (10 patients) that had required treatment for a narrowed anterior capsule opening after cataract surgery. All patients had had continuous curvilinear capsulorhexis and phacoemulsification with implantation of an intraocular lens in the capsular bag. Specimens of surgically removed fibrous membrane were examined by histopathological methods.
Fibrous membrane on the inner surface of the anterior capsule and the linear folds of the anterior capsule were present in each eye. In 10 eyes of 8 patients, the fibrous membrane was on the outer surface of the anterior capsule and covered the capsular folds at its margin. Pathological study showed that this fibrous membrane consisted of the flattened lens epithelial cells that proliferated on the inner and outer surfaces of the shrunken anterior capsule. The outgrowth of this membrane from the margin of the anterior capsule to the center of the opening of the anterior capsule was noted.
In this study, capsule contraction syndrome involved contraction of the fibrous membrane as well as its outgrowth from the capsule margin.
确定囊膜收缩综合征的发病机制是否涉及纤维膜从前囊边缘长出。
东京庆应义塾大学医学院眼科以及日本神奈川县安藤眼科诊所。
对12只眼（10例患者）进行回顾性病历及裂隙灯照片分析，这些患者在白内障手术后因前囊开口狭窄而需要治疗。所有患者均行连续环形撕囊及超声乳化白内障吸除术，并在囊袋内植入人工晶状体。采用组织病理学方法检查手术切除的纤维膜标本。
每只眼中均可见前囊内表面的纤维膜及前囊的线性皱襞。8例患者的10只眼中，纤维膜位于前囊外表面，并在其边缘覆盖囊膜皱襞。病理研究表明，该纤维膜由在皱缩的前囊内、外表面增殖的扁平晶状体上皮细胞组成。观察到该膜从前囊边缘向前囊开口中心生长。
在本研究中，囊膜收缩综合征涉及纤维膜的收缩及其从囊膜边缘的生长。
