Lam D S, Leung A T, Wu J T, Fan D S, Cheng A C, Wang Z
Prince of Wales Hospital, Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Shatin, NT, China.
J Cataract Refract Surg. 1999 Jul;25(7):1004-8. doi: 10.1016/s0886-3350(99)00080-2.
A 40-year old man, highly myopic in both eyes, had laser in situ keratomileusis (LASIK) in the left eye in November 1996. Corneal melting and ulceration and fine striae-like interface infiltrates were noticed 1 day postoperatively. There was no response to intensive topical antibiotics in the form of hourly ofloxacin 3% (Tarivid), and satellite lesions developed on day 4. Corneal scrapings for gram stain and culture were done twice. No bacterial or fungal organisms were identified. Intensive topical fortified vancomycin (50 mg/mL) was added, and the lesions resolved gradually over the ensuing 2 weeks. Eighteen months after LASIK, refraction was -1.50 - 0.75 x 105 in the left eye, and uncorrected visual acuity was 20/70, correctable to 20/25 with spectacles.
一名40岁男性，双眼高度近视，于1996年11月在左眼行准分子激光原位角膜磨镶术（LASIK）。术后1天发现角膜溶解、溃疡及细微条纹状界面浸润。每小时使用3%氧氟沙星（泰利必妥）进行强化局部抗生素治疗无效，术后第4天出现卫星病灶。角膜刮片进行革兰氏染色和培养2次。未鉴定出细菌或真菌。加用强化局部万古霉素（50mg/mL），随后2周内病灶逐渐消退。LASIK术后18个月，左眼验光为-1.50 - 0.75×105，未矫正视力为20/70，戴眼镜可矫正至20/25。
