Beaulieu C, D'Arceuil H, Hedehus M, de Crespigny A, Kastrup A, Moseley M E
Lucas MRI Center, Department of Radiology, Stanford University, CA, USA.
Semin Pediatr Neurol. 1999 Jun;6(2):87-100. doi: 10.1016/s1071-9091(99)80035-7.
Magnetic resonance imaging (MRI) is an excellent tool for the investigation of neurological disorders in children. Diffusion-weighted MRI (DWI) is sensitive to the diffusion (or molecular displacement) of water in tissue. The purpose of this article is to describe briefly the basic theory behind DWI and to discuss its potential applications to neurological disorders in children. We demonstrate that DWI is a sensitive technique for the detection of acute brain injury, and that it is well suited for monitoring brain development, particularly myelination and white matter changes.
磁共振成像（MRI）是用于研究儿童神经系统疾病的一项出色工具。弥散加权磁共振成像（DWI）对组织中水分子的扩散（或分子位移）敏感。本文旨在简要描述DWI背后的基本理论，并探讨其在儿童神经系统疾病中的潜在应用。我们证明，DWI是检测急性脑损伤的一项敏感技术，且非常适合监测脑发育，尤其是髓鞘形成和白质变化。
