Weir S C, Gibert C L, Gordin F M, Fischer S H, Gill V J
Microbiology Service, Clinical Pathology Department, National Institutes of Health, Bethesda, Maryland 20892, USA.
J Clin Microbiol. 1999 Aug;37(8):2729-33. doi: 10.1128/JCM.37.8.2729-2733.1999.
An unusual Helicobacter sp. was isolated from the blood of a human immunodeficiency virus (HIV)-infected patient. This organism had spiral morphology, with single amphitrichous flagella, and was negative for hippurate hydrolysis, production of urease, and reduction of nitrate. 16S rRNA gene sequence analysis verified that the isolate was a species of Helicobacter, most closely related to an undescribed Helicobacter-like isolate from Vancouver, British Columbia, Canada, and to Helicobacter westmeadii, a recently described species from Australia. Both organisms had also been isolated from the blood of HIV-infected patients. These blood isolates, along with Helicobacter cinaedi, form a cluster of closely related Helicobacter spp. that may represent an emerging group of pathogens in immunocompromised patients.
从一名感染人类免疫缺陷病毒(HIV)的患者血液中分离出一种不寻常的螺杆菌属细菌。该微生物呈螺旋形态,有单端双鞭毛,马尿酸盐水解、尿素酶产生及硝酸盐还原试验均为阴性。16S rRNA基因序列分析证实该分离株是螺杆菌属的一个种,与来自加拿大不列颠哥伦比亚省温哥华的一株未描述的类螺杆菌分离株以及来自澳大利亚的最近描述的韦氏螺杆菌关系最为密切。这两种微生物也都从感染HIV患者的血液中分离得到。这些血液分离株与辛内迪螺杆菌一起,形成了一组密切相关的螺杆菌属细菌,它们可能代表了免疫功能低下患者中一种新出现的病原体群体。