D'Hermies F, Korobelnik J F, Chauvaud D, Pouliquen Y, Parel J M, Renard G
Ophthalmic Pathology Laboratory, Hôtel-Dieu, Paris, France.
Acta Ophthalmol Scand. 1999 Jun;77(3):279-85. doi: 10.1034/j.1600-0420.1999.770307.x.
To investigate scleral and episcleral histological alterations induced by encircling explants used in scleral buckling procedures.
We performed a histopathological study of 20 enucleated eyes after failure of retinal detachment surgery including encircling scleral buckle.
Nonabsorbable materials were encapsulated and often gave rise to a limited scleral invagination. The inner capsular surface was regular in 10 silicone explants, it was partially covered with hydrogel fragments and a granulomatous foreign body giant cell reaction in 8 hydrogel explants. One Arruga thread was encased in fibrosis and a catgut circle showed no encapsulation. Other changes were mostly related to the long-standing retinal detachment: peripheral anterior synechiae, anterior uveal effusion, persistent retinal detachment, retinal gliosis, retinal atrophy, retinal breaks, and silicone oil droplets.
All nonabsorbable explants underwent encapsulation and prompted scleral invagination. A granulomatous reaction accompanied hydrogel fragmentation. The long term fragmentation impact on implanted eyes remains unknown.
研究巩膜扣带手术中使用的环扎外植体引起的巩膜和巩膜上组织学改变。
我们对20只视网膜脱离手术（包括环扎巩膜扣带术）失败后的眼球摘除标本进行了组织病理学研究。
不可吸收材料被包裹，常导致局限性巩膜内陷。10个硅胶外植体的囊内表面规则，8个水凝胶外植体的囊内表面部分被水凝胶碎片覆盖，并伴有肉芽肿性异物巨细胞反应。一根阿鲁加线被纤维组织包裹，而一段肠线未被包裹。其他改变大多与长期视网膜脱离有关：周边前粘连、前葡萄膜渗漏、持续性视网膜脱离、视网膜胶质增生、视网膜萎缩、视网膜裂孔和硅油滴。
所有不可吸收外植体均被包裹并引起巩膜内陷。水凝胶破碎伴有肉芽肿反应。长期破碎对植入眼的影响尚不清楚。
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