Marshall J K, Collins S M, Gafni A
Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Am J Gastroenterol. 1999 Jul;94(7):1841-6. doi: 10.1111/j.1572-0241.1999.01215.x.
Upper gastrointestinal hemorrhage (UGIH) is common, and thus imposes a substantial burden on health care resources. We describe resource utilization and cost for management of acute nonvariceal UGIH, and studied their variation among population subgroups.
Resource utilization and direct medical case costs were extracted for consecutive admissions for nonvariceal UGIH at a large community hospital in southern Ontario through chart review and adaptation of an administrative case cost database. Univariate and multiple regression models were then developed to identify independent demographic predictors of case cost and length of stay.
Among 116 eligible admissions the average length of stay and case cost were 4.26 days and Can$2690, respectively (Can$1 = US$0.70). Both cost and length of stay demonstrated significant univariate relationships with age, comorbid illness, prior peptic ulcer disease (PUD), and prior UGIH. Age and prior PUD persisted as independent predictors in multiple regression models. An inverse transformation of total case cost allowed these variables to explain 26% of the total variance.
Resource utilization for management of acute nonvariceal UGIH at a Canadian community hospital varies substantially among population subgroups, but correlates independently with age and prior ulcer history. Careful attention must be paid to practice environments and demographic profiles before economic models of strategies to prevent or treat UGIH are applied to specific subpopulations.
上消化道出血(UGIH)很常见,因此给医疗资源带来了沉重负担。我们描述了急性非静脉曲张性UGIH管理的资源利用情况和成本,并研究了其在不同人群亚组中的差异。
通过病历审查和改编行政病例成本数据库,提取了安大略省南部一家大型社区医院连续收治的非静脉曲张性UGIH患者的资源利用情况和直接医疗病例成本。然后建立单变量和多变量回归模型,以确定病例成本和住院时间的独立人口统计学预测因素。
在116例符合条件的入院患者中,平均住院时间和病例成本分别为4.26天和2690加元(1加元 = 0.70美元)。成本和住院时间在单变量分析中均与年龄、合并症、既往消化性溃疡病(PUD)和既往UGIH有显著关系。在多变量回归模型中,年龄和既往PUD仍然是独立的预测因素。病例总成本的逆变换使这些变量能够解释总方差的26%。
加拿大社区医院急性非静脉曲张性UGIH管理的资源利用在不同人群亚组中差异很大,但与年龄和既往溃疡病史独立相关。在将预防或治疗UGIH的策略的经济模型应用于特定亚人群之前,必须仔细关注实践环境和人口统计学特征。