Honda M
Department of Pediatric Nephrology, Tokyo Metropolitan Children's Hospital, Japan.
Perit Dial Int. 1999;19 Suppl 2:S473-8.
We have collected data on pediatric patients less than 16 years of age from the National Registry of Chronic Peritoneal Dialysis (PD). We present our experience with this population.
The database details the patient numbers, age, outcome, cause of death, reason for terminating PD therapy, type of PD therapy, peritonitis, and catheter survival.
Of 807 patients, 70 patients (8.7%) were under 1 year of age, and 268 patients (33.2%) were under 6 years of age, clearly indicating that PD was the treatment of choice in young children. The duration on PD was 5 years or more in 200 patients (24.8%), which showed an increase in long-term PD patients from 11% in 1991. Patients on automated PD (APD) increased to 75% in 1997 from 9% in 1991.
The outcomes for the total patient population of 807 as of the end of 1997 is: 253 patients (31.4%) were being successfully treated with PD, 87 patients (10.8%) died, 238 patients (29.5%) received a kidney transplant, and 121 (15.0%) were transferred to hemodialysis. The patient survival rate was 91% in 3 years and 86% in 5 years. The technique survival rate was 83% in 3 years and 71% in 5 years. The rate of peritonitis was 1 episode per 30 patient-months. The mean catheter duration was 2.25 years.
The patient and technique survival rates, the peritonitis rate, and the catheter survival improved recently. However, these data were worse in younger children (less than 6 years of age), indicating that extra-careful management is needed for this young age group.
我们从国家慢性腹膜透析(PD)登记处收集了16岁以下儿科患者的数据。我们展示了我们在这一人群中的经验。
该数据库详细记录了患者数量、年龄、结局、死亡原因、终止PD治疗的原因、PD治疗类型、腹膜炎和导管存活情况。
在807名患者中,70名患者(8.7%)年龄在1岁以下,268名患者(33.2%)年龄在6岁以下,这清楚地表明PD是幼儿的首选治疗方法。200名患者(24.8%)接受PD治疗的时间为5年或更长,这表明长期PD患者从1991年的11%有所增加。接受自动化腹膜透析(APD)的患者从1991年的9%增加到1997年的75%。
截至1997年底,807名患者的总体结局为:253名患者(31.4%)接受PD治疗成功,87名患者(10.8%)死亡,238名患者(29.5%)接受了肾移植,121名患者(15.0%)转为血液透析。3年患者生存率为91%,5年为86%。3年技术生存率为83%,5年为71%。腹膜炎发生率为每30患者月1次。导管平均使用时长为2.25年。
患者和技术生存率、腹膜炎发生率和导管存活率最近有所改善。然而,这些数据在年幼儿童(6岁以下)中更差,表明这一年龄组需要格外谨慎的管理。