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恒河猴(猕猴)体内蠕虫感染的发病率、发病机制及治疗方法。

The incidence, pathogenesis and treatment of helminth infections in rhesus monkeys (Macaca mulatta).

作者信息

Remfry J

出版信息

Lab Anim. 1978 Oct;12(4):213-8. doi: 10.1258/002367778781088440.

Abstract

In a survey of 259 newly-imported rhesus monkeys, 5 species of nematode parasites were commonly found. Of these 5 species, Oesophagostomum spp. and Strongyloides fulleborni were implicated in the deaths of 3 monkeys. 5 other nematode species, 2 cestode species and 1 trematode species were also found; their pathogenicity is discussed. The results of treatment of parasitic infections with 6 different drugs is reported. Thiabendazole at an initial dose of 100 or 133 mg/kg and repeated at 50 mg/kg was found to be the most effective treatment against Oesophagostomum spp.

摘要

在一项对259只新引进的恒河猴的调查中,共发现5种线虫寄生虫。在这5种线虫中,结节线虫属和富氏类圆线虫导致了3只猴子死亡。还发现了另外5种线虫、2种绦虫和1种吸虫;文中讨论了它们的致病性。报告了用6种不同药物治疗寄生虫感染的结果。发现初始剂量为100或133毫克/千克、然后以50毫克/千克重复给药的噻苯达唑是治疗结节线虫属的最有效药物。

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