Barrera-Ramírez C F, Barragán-Campos H M, Sánchez-Guerrero J, García-Ramos G, Vega-Boada F, Estañol B
Instituto Nacional de Cardiología I gnacio Chávez, México D.F.
Rev Invest Clin. 1999 Mar-Apr;51(2):121-34.
The investigations of mitochondrial DNA abnormalities and its relationship with derangements of oxidative phosphorylation and electron transport system, has yielded description a myriad of syndromes called mitochondrial diseases or cytopathies. The objective of this paper is to review the clinical relevant features of this heterogeneous group of diseases, to understand the board spectrum of signs and symptoms and suggest an algorithm for the diagnosis.
对线粒体DNA异常及其与氧化磷酸化和电子传递系统紊乱关系的研究，已经描述了无数种被称为线粒体疾病或细胞病的综合征。本文的目的是回顾这一异质性疾病组的临床相关特征，了解其广泛的体征和症状谱，并提出一种诊断算法。
