Schleef J, Wagner A, Kleta R, Schaarschmidt K, Dockhorn-Dworniczak B, Willital G, Jürgens H
Department of Pediatric Hematology and Oncology, WW University of Münster, Germany.
Pediatr Surg Int. 1999 Jul;15(5-6):431-4. doi: 10.1007/s003830050625.
Tumors of the ovary in girls represent about 80% of pediatric genital tumors; approximately 30% of these tumors are malignant. The risk of malignancy increases with decreasing age. The most frequent finding is a teratoma; other tumors are rare. Small-cell carcinoma (SCCO) of the ovary is extremely rare, occurring mostly in young women. We present an 8-year-old girl with a SCCO of the hypercalcemic type. The findings and treatment are discussed with emphasis on the poor prognosis in these patients, even in stage 1 disease. The current literature is reviewed.
女童卵巢肿瘤约占小儿生殖系统肿瘤的80%;其中约30%为恶性肿瘤。恶性风险随年龄降低而增加。最常见的是畸胎瘤;其他肿瘤较为罕见。卵巢小细胞癌(SCCO)极为罕见,多见于年轻女性。我们报告一名8岁患有高钙血症型SCCO的女童。讨论了其检查结果及治疗方法,重点强调了这些患者即使处于1期疾病,预后也较差。并对当前文献进行了综述。