Rolland N, Grandbastien B, Merle V, Gower-Rousseau C, Yzet T, Marti R, Lerebours E, Dupas J L, Czernichow P, Salomez J L, Lebrun T, Cortot A
CRESGE-Centre de Recherches Economiques Sociologiques et de Gestion, Lille, France.
Gastroenterol Clin Biol. 1999 Apr;23(4):483-8.
The aim of this study was to assess the cost of the first management of inflammatory bowel disease (IBD) from the onset of first symptoms until 6 weeks after the diagnosis. This cost was calculated in French francs (FF) for all IBD and namely for Crohn's disease (CD), ulcerative colitis (UC), and ulcerative proctitis (UP).
Data concerning 258 patients were collected by the mean of a standardized questionnaire from 3 different sources: the patient, his general practitioner, and his gastroenterologist.
Two hundred and fifty eight patients were included: 144 CD (55.8%), 76 UC (29.5%), 30 UP (11.6%), and 8 chronic unclassifiable colitis (CUC) (3.1%). The mean direct costs of the diagnosis (m +/- SD) were 23,116 +/- 40,820 FF for CD, 10,628 +/- 17,316 FF for UC and 3,451 +/- 2,743 FF for UP. Although unplanned hospitalizations occurred in only 38% of the patients (98/258), they represented the 3/4 of the mean costs: 78.2% for CD and 64% for UC. Indirect costs generated by days off work were 4,719 +/- 6,610 FF for CD, 2,996 +/- 6,897 FF for UC and 1,230 +/- 3,622 FF for UP.
The first management of a patient with CD was twice more expensive than the one with UC and 6.5 times than the one with UP.
本研究旨在评估从首次出现症状开始至确诊后6周内炎症性肠病（IBD）首次治疗的费用。以法国法郎（FF）计算所有IBD患者的此项费用，尤其是克罗恩病（CD）、溃疡性结肠炎（UC）和溃疡性直肠炎（UP）患者。
通过一份标准化问卷从3个不同来源收集了258例患者的数据：患者本人、其全科医生和胃肠病学家。
纳入258例患者：144例CD（55.8%），76例UC（29.5%），30例UP（11.6%），8例慢性不可分类结肠炎（CUC）（3.1%）。CD患者诊断的平均直接费用（m±SD）为23,116±40,820 FF，UC患者为10,628±17,316 FF，UP患者为3,451±2,743 FF。尽管只有38%的患者（98/258）发生了非计划性住院，但这些住院费用占平均费用的3/4：CD患者为78.2%，UC患者为64%。因误工产生的间接费用，CD患者为4,719±6,610 FF，UC患者为2,996±6,897 FF，UP患者为1,230±3,622 FF。
CD患者的首次治疗费用比UC患者贵两倍，比UP患者贵6.5倍。
