Lambert R, Jacob P
I. Spécialités digestives hôpital Edouard-Herriot, Lyon.
Rev Prat. 1999 Jun 1;49(11):1166-71.
Oesophageal cancer includes two distinct tumours: squamous cell cancer is related to alcohol and tobacco consumption; adenocarcinoma develops on a metaplastic columnar mucosa lining the oesophagus (Barrett's oesophagus). In Western countries the ratio of the 2 tumors is 6 to 4. Dysphagia is a late symptom in the evolution and corresponds in most cases to advanced cancer with poor prognosis. Treatment decision required evaluation of the performance status, search for associated tumors (mouth, pharynx and respiratory tract), and evaluation of the locoregional extension of the primary tumour. In the absence of dysphagia, detection of oesophageal cancer at an early stage is compatible with a curative option.
鳞状细胞癌与饮酒和吸烟有关；腺癌发生在食管内衬的化生柱状黏膜（巴雷特食管）上。在西方国家，这两种肿瘤的比例为6比4。吞咽困难是疾病进展中的晚期症状，在大多数情况下与预后不良的晚期癌症相对应。治疗决策需要评估身体状况、寻找相关肿瘤（口腔、咽部和呼吸道）以及评估原发肿瘤的局部区域扩展情况。在没有吞咽困难的情况下，早期发现食管癌适合采用治愈性治疗方案。
