Benchimol D, Baqué P
Service de chirurgie abdominale et thoracique, Hôpital l'Archet II, Nice.
Rev Prat. 1999 Jun 1;49(11):1172-6.
Squamous cell carcinoma of the oesophagus has a poor prognosis, owing in part to the compromised status of the patients. Early oesophageal cancer is rarely diagnosed, even if its endoscopic aspects are well known. From the mucosa, the disease progresses step by step, and also via the submucosa. Furthermore, multiple locations are not uncommon. Bulky tumours progressively obstruct the oesophageal lumen while infiltrative tumours invade the oesophageal layers, and then the perioesophageal fat and the mediastinal organs. Involvement of mediastinal, cervical and abdominal lymph nodes occurs early. Distant metastases occur later. Complications are mainly due to the locoregional spread of the disease, leading to death.
食管癌鳞状细胞癌预后较差，部分原因是患者身体状况不佳。早期食管癌即使其内镜表现广为人知，也很少被诊断出来。该疾病从黏膜开始，逐步进展，也会通过黏膜下层扩散。此外，多部位发病并不少见。体积较大的肿瘤会逐渐阻塞食管腔，而浸润性肿瘤会侵犯食管各层，进而侵犯食管周围脂肪和纵隔器官。纵隔、颈部和腹部淋巴结早期就会受累。远处转移较晚出现。并发症主要是由于疾病的局部区域扩散导致死亡。
