Knowles P R, Randall N P, Lockhart A S
Department of Anaesthesia, Blackpool Victoria Hospital, UK.
Anaesthesia. 1999 Jul;54(7):647-50. doi: 10.1046/j.1365-2044.1999.00957.x.
Samples of cerebrospinal fluid obtained from 130 patients undergoing spinal anaesthesia were examined microscopically. Subarachnoid puncture was performed using either a 25G Whitacre or 25G Quincke spinal needle. Two samples were collected from each patient and the red blood cell count of the second sample collected was taken as a measure of the vascular trauma associated with the procedure. Red blood cells were seen in 50 (38%) of these samples, of which 18 (14%) contained > 100 red blood cells.mm-3. Paraesthesia was felt by 11 (8.5%) patients and the occurrence of paraesthesia was associated with significantly raised red blood cell counts (p < 0.0001). There was also a correlation between the number of needle passes made at lumbar puncture and the red blood cell count in the sample (p < 0. 0001). Neither spinal needle type nor antiplatelet drug therapy influenced red blood cell counts (p = 0.66 and 0.37, respectively). These findings suggest that routine spinal anaesthesia is often complicated by minor degrees of vascular trauma, especially when paraesthesiae or technical difficulty occur at subarachnoid puncture.
对130例接受脊髓麻醉的患者获取的脑脊液样本进行了显微镜检查。蛛网膜下腔穿刺使用25G惠特克或25G奎克脊髓穿刺针进行。从每位患者收集两份样本,将收集的第二份样本中的红细胞计数作为与该操作相关的血管创伤的指标。在这些样本中有50份(38%)可见红细胞,其中18份(14%)每立方毫米含有超过100个红细胞。11名(8.5%)患者感到感觉异常,感觉异常的发生与红细胞计数显著升高相关(p<0.0001)。腰椎穿刺时穿刺针穿刺次数与样本中的红细胞计数之间也存在相关性(p<0.0001)。脊髓穿刺针类型和抗血小板药物治疗均未影响红细胞计数(p分别为0.66和0.37)。这些发现表明,常规脊髓麻醉常伴有轻度血管创伤,尤其是在蛛网膜下腔穿刺出现感觉异常或技术困难时。