Schuster J M, Roberts T S
Department of Neurological Surgery, University of Washington, Seattle, Wash., USA.
Pediatr Neurosurg. 1999 Apr;30(4):206-10. doi: 10.1159/000028797.
Noonan's syndrome is a multiple congenital anomaly syndrome with characteristic facial features, short stature, congenital heart defects and a recently reported association with moyamoya disease. We report a case of symptomatic moyamoya disease and aortic coarctation in a patient with Noonan's syndrome. The case illustrates the need for a rational, coordinated treatment plan for dealing with the cardiac and neurologic syndromic anomalies to help avoid undesirable outcomes.
努南综合征是一种多发性先天性异常综合征，具有特征性面部特征、身材矮小、先天性心脏缺陷，且最近报道与烟雾病有关。我们报告了1例努南综合征患者出现症状性烟雾病和主动脉缩窄的病例。该病例表明，需要制定合理、协调的治疗方案来处理心脏和神经综合征性异常，以避免不良后果。
