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[胃癌。通过胃置换或胃次全切除术优化治疗?]

[Stomach carcinoma. Optimizing therapy by stomach replacement or subtotal resection?].

作者信息

Meyer H J, Opitz G J

机构信息

Klinik für Allgemein- und Viszeralchirurgie, Städtisches Klinikum Solingen.

出版信息

Zentralbl Chir. 1999;124(5):381-6.

Abstract

The extent of surgical resection in the treatment of gastric carcinoma depends on the tumor site as well as on the histomorphological type according to Lauren taking into account the margins of clearance at the oral resection line. Following subtotal distal gastrectomy functional long-term results might be generally better in comparison to total gastrectomy. Among the large variety of operative methods of reconstruction after total gastrectomy the Roux-en-Y procedure is preferred by the majority of surgeons. Nevertheless, according to experimental and clinical trials jejunal interposition technique seems to allow a more physiological gastric replacement with improved postoperative function and quality of life. Furthermore, jejunal interposition can influence the motility of the entire intestinal tract resulting in a better functional outcome. The importance of pouches for gastric substitute with positive impact on the long-term nutritional status must be clarified in further clinical trials. In conclusion, the question of ideal mode of reconstruction of the upper gastrointestinal tract is still open and continues to be found out.

摘要

胃癌治疗中手术切除的范围取决于肿瘤部位以及根据劳伦分类法的组织形态学类型,并需考虑近端切除线的切缘。与全胃切除术相比,远端胃次全切除术后的长期功能结果通常可能更好。在全胃切除术后的多种重建手术方法中,大多数外科医生更倾向于采用Roux-en-Y手术。然而,根据实验和临床试验,空肠间置技术似乎能实现更符合生理的胃替代,改善术后功能和生活质量。此外,空肠间置可影响整个肠道的蠕动,从而带来更好的功能结果。胃替代袋对长期营养状况有积极影响,其重要性有待进一步临床试验阐明。总之,上消化道理想的重建方式问题仍未解决,有待继续探索。

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