[The nature of the relationships between the dynamics of local interneuronal connections and of the total bioelectrical activity of the frontal cortex in the dog].

Temporal patterns of correlated firings were studied in small groups of neurons simultaneously recorded in the frontal cortex of a behaving dog. To identify the character of relations between the patterns of interneuronal connections in local ensembles and event-related potentials (ERP), the following procedure was applied. At the first step, single trials of behavioral task were classified by clustering temporal distribution of correlated firings in pairs of units. Then the surface ERP were averaged separately for each cluster and parameters of the ERP components were compared between the clusters. The analysis revealed 3 of 7 recording sites, where significant differences were observed between the ERP sampled from the clusters with different structures of the local interneuronal connections. The results suggest that temporal modulation of interactions between neurons in local ensembles reflects a large-scale reorganization of cortical networks.