大鼠脑内磁性铁生物矿化：铁负荷的影响。

Magnetic iron biomineralization in rat brains: effects of iron loading.

作者信息

Pardoe H, Dobson J

机构信息

Department of Physics, University of Western Australia, Nedlands, Perth, Australia.

出版信息

Biometals. 1999 Mar;12(1):77-82. doi: 10.1023/a:1009231414699.

DOI:10.1023/a:1009231414699

PMID:10420577

Abstract

Isothermal remanent magnetization was measured in 14 Wistar and five Porton rat brains. Results indicate that magnetic iron biominerals are present in most of the samples and the formation of these minerals in the rat brain is influenced by transfusion and dietary iron loading when compared to control samples. The high level of consistency in the concentrations and the lack of magnetic material in several of the measured samples indicates that a genetic mechanism may be responsible for magnetic iron biomineralization in the rat brain. Comparison with human studies indicates that extrapolation of the results of rat studies of electromagnetic field bioeffects may not be accurately extrapolated to humans in all cases.

摘要

在14只Wistar大鼠和5只Porton大鼠的大脑中测量了等温剩余磁化强度。结果表明，大多数样本中存在磁性铁生物矿物，与对照样本相比，大鼠大脑中这些矿物的形成受输血和饮食中铁负荷的影响。几个测量样本中浓度的高度一致性以及磁性物质的缺乏表明，遗传机制可能是大鼠大脑中磁性铁生物矿化的原因。与人体研究的比较表明，在所有情况下，大鼠电磁场生物效应研究结果可能无法准确外推至人类。