Püllen R
III. Med. Klinik der Kliniken St. Antonius, Geriatrische Klinik für die Universität Witten/Herdecke, Velbert.
Versicherungsmedizin. 1999 Jun 1;51(2):71-4.
Many elderly patients are prescribed psychotropic medication, many of them are car drivers. Driving ability may be impaired by the underlying psychiatric disease, the medication or the combination of both. Psychoactive medications do not all influence driving ability to the same extent. Cyclic antidepressants impair driving performance to a higher degree than selective serotonin reuptake inhibitors (SSRI) or MAO inhibitors. In cases of severe psychiatric diseases like major depression an appropriate psychoactive medication may improve driving performance. The influence of psychoactive drugs on driving ability is not always taken into account. There are no data available that allow a reliable assessment of these drugs in elderly patients. To meet the challenge of this problem, patients and doctors have to be aware of this problem; studies about the impact of psychoactive drugs on driving ability are necessary.
许多老年患者都被开了精神类药物，其中很多人是汽车司机。驾驶能力可能会受到潜在精神疾病、药物或两者共同作用的损害。精神活性药物对驾驶能力的影响程度不尽相同。三环类抗抑郁药比选择性5-羟色胺再摄取抑制剂（SSRI）或单胺氧化酶抑制剂对驾驶表现的损害程度更高。在患有严重精神疾病如重度抑郁症的情况下，适当的精神活性药物可能会改善驾驶表现。精神活性药物对驾驶能力的影响并非总是被考虑在内。目前尚无数据能够可靠评估这些药物对老年患者的影响。为应对这一问题带来的挑战，患者和医生必须意识到这个问题；有必要开展关于精神活性药物对驾驶能力影响的研究。
