Pandrea I, Creţu O, Apetrei C, Creţu I, Fluture V, Mihailovici M S
Centre Hépato-Biliaire, Hôpital Paul Brousse, Villejuif, Franţa.
Chirurgia (Bucur). 1998 Nov-Dec;93(6):375-86.
Hepatic graft rejection is an epiphenomenon of liver transplantation. Despite the immunosuppressive therapy, nowadays a level of 30-50% of acute rejection and 5-15% chronic rejection is always persisting. Graft rejection prophylaxis essentially represents the result of a subtle equilibrium of the chronic immunosuppression. This study presents the essential data concerning the graft rejection, such as: prevalences, classifications, clinical presentation and diagnostic, both anatomopathological and differential. Modern therapy of hepatic graft rejection is also presented.
肝移植排斥反应是肝移植的一种附带现象。尽管采用了免疫抑制疗法，但如今仍有30% - 50%的急性排斥反应和5% - 15%的慢性排斥反应持续存在。移植物排斥反应的预防本质上是慢性免疫抑制微妙平衡的结果。本研究呈现了有关移植物排斥反应的基本数据，如：患病率、分类、临床表现及诊断，包括解剖病理学诊断和鉴别诊断。还介绍了肝移植排斥反应的现代治疗方法。
