Cacy J, Mold J W
Department of Family and Preventive Medicine, the University of Oklahoma, Oklahoma City 73104, USA.
J Fam Pract. 1999 Jul;48(7):536-42.
The brown recluse spider (Loxosceles reclusa) has been recognized as a cause of necrotizing bites since at least 1957, but most of the literature consists of laboratory studies using animals, human sera, or case reports of more dramatic examples of bite reactions. Our goal was to develop a more comprehensive clinical description of the brown recluse spider bites treated by family physicians.
Two preprinted, postage-paid cards were given to physician members of the Oklahoma Physicians Research Network. One card was used for recording examination and treatment data, and the other was for tracking the progress of the bite until it was completely healed. For comparison, similar information was collected from the local poison control center.
From April 1996 to August 1998, the physicians recorded 149 bites. Most of the victims were women aged 18 to 65 years, and most sought treatment within 3 days. Pain was common but not universal. Most bites were located on the extremities. Erythema was always present, but necrosis was present in only 40% of the bites. Some systemic signs or symptoms were common. The most frequent forms of treatment were systemic antibiotics (66% of cases) and conservative wound management (56%). Only 1 hospitalization occurred; 43% of the bites healed within 2 weeks; and only 13% resulted in scarring.
The brown recluse spider bite is a relatively common problem treated by family physicians in Oklahoma. Most bites are not serious. More research at the practice level is needed to develop diagnostic criteria and to explore the effectiveness of various treatment options.
至少自1957年以来,棕色遁蛛(褐蛛)已被确认为坏死性咬伤的病因,但大多数文献都是关于使用动物、人类血清的实验室研究,或咬伤反应更显著案例的病例报告。我们的目标是对家庭医生治疗的棕色遁蛛咬伤进行更全面的临床描述。
向俄克拉荷马州医师研究网络的医师成员发放了两张预先印制、已付邮资的卡片。一张卡片用于记录检查和治疗数据,另一张用于跟踪咬伤的进展直至完全愈合。为作比较,从当地毒物控制中心收集了类似信息。
1996年4月至1998年8月,医师们记录了149例咬伤。大多数受害者为18至65岁的女性,大多数在3天内寻求治疗。疼痛很常见但并非普遍存在。大多数咬伤位于四肢。红斑总是存在,但只有40%的咬伤出现坏死。一些全身症状很常见。最常见的治疗方式是全身使用抗生素(66%的病例)和保守的伤口处理(56%)。仅发生了1例住院治疗;43%的咬伤在2周内愈合;只有13%的咬伤导致瘢痕形成。
棕色遁蛛咬伤是俄克拉荷马州家庭医生治疗的相对常见问题。大多数咬伤并不严重。需要在实践层面进行更多研究以制定诊断标准并探索各种治疗方案的有效性。