Sabaté J M, Gaudric M, Dousset B, Chaussade S, Couturier D
Service de Gastroentérologie, Hôpital Cochin, Paris.
Gastroenterol Clin Biol. 1999 May;23(5):573-6.
Esophageal involvement is frequent in Down syndrome. We report a case of dysphagia in a 21-year-old patient with Down syndrome and repaired esophageal atresia. Radiology, endoscopy, and manometry showed typical features of achalasia. The patient was treated first by botulinum toxin injection and afterwards by Heller myotomy with good result. The role of motor disorders associated with esophageal atresia or with primary achalasia in this patient is discussed.
唐氏综合征患者常伴有食管受累。我们报告一例21岁唐氏综合征患者，其患有食管闭锁修补术后出现吞咽困难。放射学、内镜检查和测压显示出贲门失弛缓症的典型特征。该患者首先接受肉毒杆菌毒素注射治疗，随后进行了Heller肌切开术，效果良好。本文讨论了该患者中与食管闭锁或原发性贲门失弛缓症相关的运动障碍的作用。
