Den Otter W, Balemans L, Battermann J J, Bernsen M R, Cadee J A, Dobrowolski Z, Everse L A, Fiszer-Maliszewska L, Gavhumende R, De Groot J W, De Groot K, Hennink W E, Hill F W, Jurgenliemp-Schulz I, Klein W R, Koten J W, Maas R A, Steerenberg P, Stewart R, Zembala M
Department of Cell Biology, Utrecht University, The Netherlands.
Hepatogastroenterology. 1999 May;46 Suppl 1:1280-6.
Interleukin-2 (IL-2) is a powerful drug for treating cancer. However, it is only powerful if it is properly applied. That is, IL-2 should be applied at the tumor site, because at the transition of normal and malignant tissue are the tumor infiltrating cells. These should be activated by IL-2. Local application implies that IL-2 can be used in relatively low doses. It is becoming clear that even a single injection of IL-2 can cure cancer. IL-2 can also enhance the therapeutic effects of irradiation and Cisplatin. Locally applied IL-2 therapy is virtually non-toxic.
白细胞介素-2（IL-2）是一种治疗癌症的强效药物。然而，只有正确应用它才会强效。也就是说，IL-2应该应用于肿瘤部位，因为在正常组织与恶性组织的交界处存在肿瘤浸润细胞。这些细胞应该被IL-2激活。局部应用意味着IL-2可以以相对低的剂量使用。越来越明显的是，即使单次注射IL-2也可以治愈癌症。IL-2还可以增强放疗和顺铂的治疗效果。局部应用IL-2疗法几乎没有毒性。
