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Lack of transmission of hepatitis C virus following needlestick accidents.

作者信息

Hasan F, Askar H, Al Khalidi J, Al Shamali M, Al Kalaoui M, Al Nakib B

机构信息

Thunayan Al-Ghanim Gastroenterology and Hepatology Center, and Amiri Hospital, Kuwait.

出版信息

Hepatogastroenterology. 1999 May-Jun;46(27):1678-81.

PMID:10430320
Abstract

Healthcare workers (HCWs) have an occupational risk of infection with hepatitis C virus (HCV). However, data regarding the magnitude of this risk are limited. We conducted a prospective study on a cohort of 24 HCWs who were exposed to HCV by needlestick injuries involving 25 patients. All source patients were viremic with a mean HCV-RNA level of 1.65 megagenomic equivalents per milliliter. At least 64% of patients were infected with HCV serotype 4 (Simmond's classification). After a follow up period of at least 6 months, none of the exposed HCWs acquired HCV. Thus, HCV does not seem to be easily transmitted by needlestick injuries. However, further large-scale studies are needed for a more accurate estimation of the risk of transmission.

摘要

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