Hourihane J M, Clark W M
Department of Neurology, Oregon Stroke Center, Oregon Health Sciences University, Portland, Oregon 97201, USA.
Neuroimaging Clin N Am. 1999 Aug;9(3):539-52.
This article reviews both the commonly used functional outcome scales and the detailed neurologic deficit scales that are currently employed in stroke therapeutic efficacy trials. Both types of scales have their apparent advantages, with the neurologic scales being able to detect smaller changes in the patient's neurologic function, whereas the functional outcome scales appear to have more relevance to the patient's ability to function independently. Clearly, both types of scales also possess weaknesses, and to date there is no agreement on a single gold standard for measuring a drug's therapeutic efficacy after a stroke.
本文回顾了目前用于中风治疗疗效试验的常用功能结局量表和详细神经功能缺损量表。这两种量表都有其明显的优点，神经功能量表能够检测出患者神经功能的较小变化，而功能结局量表似乎与患者独立功能的能力更相关。显然，这两种量表也都有缺点，并且迄今为止，对于中风后测量药物治疗疗效的单一金标准尚无共识。
