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New hexahydrocarbazoles and spiro indoles, and their affinity for D2 dopamine and 5-HT2A serotonin receptors.

作者信息

Fernández F, García-Mera X, Rodríguez G, Urrutia A

机构信息

Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago, Santiago de Compostela, Spain.

出版信息

Chem Pharm Bull (Tokyo). 1999 Jul;47(7):1006-9. doi: 10.1248/cpb.47.1006.

DOI:10.1248/cpb.47.1006
PMID:10434402
Abstract

In a search for novel atypical antipsychotics, the synthesis of new hexahydrocarbazoles and spiro indoles N-substituted with a 3-(dimethylamino)propyl chain is described, together with the results of an in vitro evaluation of their affinities for D2 and 5-HT2A receptors.

摘要

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