Harmon D, Gardiner J, Harrison R, Kelly A
Department of Anaesthesia, Rotunda Hospital, Dublin, Ireland.
Br J Anaesth. 1999 Mar;82(3):387-90. doi: 10.1093/bja/82.3.387.
The efficacy of currently available antiemetics remains poor. Concern with their side effects and the high cost of the newer drugs has led to renewed interest in non-pharmacological methods of treatment. We have studied the efficacy of acupressure at the P6 point in the prevention of nausea and vomiting after laparoscopy, in a double-blind, randomized, controlled study of acupressure vs placebo. We studied 104 patients undergoing laparoscopy and dye investigation. The anaesthetic technique and postoperative analgesia were standardized. Failure of treatment was defined as the occurrence of nausea and/or vomiting within the first 24 h after anaesthesia. The use of acupressure reduced the incidence of nausea or vomiting from 42% to 19% compared with placebo, with an adjusted risk ratio of 0.24 (95% CI 0.08-0.62; P = 0.005). Other variables were similar between groups.
目前可用的止吐药疗效仍然欠佳。对其副作用以及新药高昂成本的担忧使得人们重新对非药物治疗方法产生兴趣。在一项关于指压与安慰剂的双盲、随机、对照研究中，我们研究了在P6穴位进行指压预防腹腔镜检查术后恶心和呕吐的疗效。我们研究了104例接受腹腔镜检查和染料检查的患者。麻醉技术和术后镇痛均标准化。治疗失败定义为麻醉后24小时内出现恶心和/或呕吐。与安慰剂相比，指压的使用使恶心或呕吐的发生率从42%降至19%，调整后的风险比为0.24（95%可信区间0.08 - 0.62；P = 0.005）。两组之间的其他变量相似。
