[Treatment of erythema migrans].

The article reviews existing clinical trials of the treatment of erythema migrans, localized early manifestation of Lyme disease. Although the treatment of this phase of Lyme disease is the best studied of all clinical manifestations, some questions remained to be answered. Author critically reviews definitions of the treatment success. Methodological diversities of the trials are emphasized. Often, treatment recommendations are not supported by existing clinical trials. Unnecessary use of antibiotics in the treatment and prophylaxis of erythema migrans is emphasized, too.