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[腹膜多囊性间皮瘤]

[Multicystic mesothelioma of the peritoneum].

作者信息

Jovović M, Savjak D, Lazović R, Vujadinović O

出版信息

Vojnosanit Pregl. 1999 Mar-Apr;56(2):217-20.

Abstract

Benign multicystic mesothelioma (MCM) of the peritoneum is a rare lesion that occurs predominantly in middle aged women with previous history of pelvic surgery. We report a case of MCM of the peritoneum in a 25-year-old man in whom cystic masses were twice surgically removed in an interval of 1.5 year. Ultrasonography and computer assisted tomography of the abdomen revealed a multicystic abdominal and pelvic mass. At first laparotomy, a multiple, thin-walled cysts ranging 0.5-7 cm in diameter were found involving the abdominal and pelvic peritoneum. After removal of all visible cysts we made histopathological diagnosis of the multilocular cavernous lymphangioma, without immunohistochemical examinations. The recurrent tumor was clinically and pathologically identical, but the final diagnosis, established upon immunohistochemical staining, was MCM: the tumor cells were strongly positive for cytokeratin, weakly positive for vimentin, and negative for Factor VIII. Management of the MCM surgical excision, unfortunately not always curative, since there is a high recurrence rate.

摘要

腹膜良性多囊性间皮瘤(MCM)是一种罕见病变,主要发生于有盆腔手术史的中年女性。我们报告一例25岁男性腹膜MCM病例,其囊性肿块在1.5年的间隔内接受了两次手术切除。腹部超声和计算机断层扫描显示腹部和盆腔有一多囊性肿块。首次剖腹手术时,发现多个直径0.5 - 7厘米的薄壁囊肿,累及腹部和盆腔腹膜。在切除所有可见囊肿后,我们未进行免疫组化检查就做出了多房性海绵状淋巴管瘤的组织病理学诊断。复发性肿瘤在临床和病理上与原肿瘤相同,但经免疫组化染色后最终诊断为MCM:肿瘤细胞细胞角蛋白呈强阳性,波形蛋白呈弱阳性,因子VIII呈阴性。MCM的治疗方法是手术切除,但遗憾的是并不总是能治愈,因为复发率很高。

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